In the course of human history drug use has developed from an intensely sacred and religious practice to an intensely secular and recreational one. The original usage of many controlled substances can be traced to the various shamans and priests within native cultures and ancient civilizations. Many of these traditions have been lost, but they still exist in records and stories. Others are still alive and flourishing, with the drug usage being celebrated and giggled at.
Cannabis has been used by Hindu gurus as early as 1500 BCE. The use of the herb is in worship of the god Shiva, also known as the supreme god. Not a bad way to worship your god as you're digging your way through a bag of crunchy Cheetos. The smoking of cannabis is said to cleanse sins, unite one with Shiva, and avoids the miseries of hell and the after-life.
Salvia divinorum, also known as the Sage of the Seers, is a herb used around Oaxaca, Mexico by shamans. These shamans take the herb in tea form, crushing the plant and infusing it with hot water, or simply chewing the leaves. It's used for religious healing ceremonies and provides the user with a psychedelic experience that can include uncontrollable laughter, becoming an object, and strange feelings of motion.
The summary, describing the sacred history of Ayahuasca, the Fly Agaric mushroom, Peyote, Damiana, Morning Glory and Hawaiian Baby Woodrose seeds, Kratom, Khat, opium, wine, and the mysterious Kykeon, continues here.