SmartshopHerbsPsychedelicSyrian rue (Peganum harmala) seeds


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Syrian rue (Peganum harmala) seeds

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Also known as esfand and harmal, Peganum harmala has an interesting Eastern history. In Turkey, dried parts from this plant are strung and hung in homes and vehicles to protect against 'the evil eye'. In Iran it is used as an incense, to purify the air as well as the mind.

In Western psycho navigation Syrian rue's strong monoamine oxidase inhibition was welcomed with open arms, offering an affordable way to potentiate high doses of DMT-bearing plant material. Many people who make ayahuasca (analogues of the psychedelic, Amazonian brew ayahuasca), use Syrian rue instead of Banisteriopsis caapi.


Common use of Syrian rue has the effect of a psychopharmacological tool, making otherwise inactive plants active. Sometimes Syrian rue is used to strengthen and prolong the effects of substances that are active by themselves. Syrian rue prevents the breakdown of monoamine neurotransmitters by inhibiting the action of monoamine oxidase enzymes, a process known as MAO-inhibition. This renders substances like DMT and 5-MeO-DMT orally active and makes a psilocybin mushroom experience last longer and become stronger.

A small number of people is experimenting with the effects of only Syrian rue infusions or smoked seeds. The effects of low doses are sometimes referred to as 'the harmala buzz', as it tends to cause a buzzing feeling throughout the head and body. This is also the initial stage for most people taking a higher dose, though it generally unfolds into a stronger experience associated with nausea, stomach cramps and vomiting. Also, psychedelic effects, such as visual and auditive distortions and mystical phenomena, seem to be common for some people.


It is possible to consume the seeds directly, by grinding them with your molars. Let the ground seeds have interplay with your saliva for half a minute up to a couple of minutes and swallow. Another way is to grind the seeds with a mortar and put the powder in gel caps. With these methods, none of the active ingredients get lost in the preparation process. For a Syrian rue only experience, doses are still experimental. People should start with 1 gram to see how they react. 5 grams is a high dose for most people.

For potentiating a normal or high dose of oral DMT, taking 3 grams of seeds 15 to 60 minutes prior to the DMT is an established method. Taking more usually results in more physical discomfort and no stronger effect. The experience will last around 4 hours. The same method can be used prior to eating mushrooms, which will make the mushrooms 1½ to 2 times stronger. It also adds 1 to 3 hours to the duration.

Another common preparation method, which is easier on the stomach and causes less nausea in general, is to make a hot water infusion. Part of the active ingredients can easily get lost in the process of this method, so add 1 to 2 grams to the doses mentioned earlier. 150 ml of water and 50 ml of lemon juice per person is used. Simmer the finely ground seeds for 15 to 30 minutes on the lowest fire on your stove and strain the liquid, which is then ready for consumption.

And finally, many people still use these seeds as an incense. In high amounts, this can also cause MAO-inhibition, albeit of shorter duration in comparison with oral ingestion.

Peganum Harmala is easy to grow. Sow the seeds in late spring (indoors) in a sandy soil mixture and be moderate with water. Put on a sunny spot and keep the temperature above 20 °C. Once your plant is all grown up (and placed outdoors) frost and dryness will not affect your plant anymore. During wintertime, the leaves will die, but the roots keep themselves in a deep hibernation, they will wake up again at the crack of spring.


The primary active ingredients in P. harmala are harmine and harmaline. (C. Raetsch 2005)


Peganum harmala contains MAO-inhibiting substances. This means it can be very dangerous when combined with certain foods or other psychoactives that are totally harmless when taken by themselves.



You can find more information, links and experiences with Peganum harmala at Erowid.

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Reviews - Syrian rue (Peganum harmala) seeds

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21 Reviews

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Lazyshaman 2012-01-29

There is this discussion: is Peganum active on its own or is it just a booster ? I decided to give it a try...So on a evening I took 15 grams fine powdered seeds with cold water and the taste wasnt that horrible as it is often reported, i think…

There is this discussion: is Peganum active on its own or is it just a booster ? I decided to give it a try...So on a evening I took 15 grams fine powdered seeds with cold water and the taste wasnt that horrible as it is often reported, i think eating Peyote is really bad "cuisine" experience.

Anyways, time passed by, after one hour I had a tipsy feeling and decided to go to bed. It was almost midnight and i made my way to the WC and when I switched the lights on, there was a golden wonderful pulsating glance covering the environment, glittering, sparkling, i saw metallic golden warm energy-strings connecting all things together, surrounding my hands- this magic and so so beautiful golden spectacle.

I got back to bed and fell in a soft mellow state between being wake and sleeping and had very vivid scenic visions, some trivial, others with a mystical depth, i felt pure energy of love going through my body and i spread it out to my parents that were sleeping next door. I imagined if complementing for example mushrooms this would go very far.

It was a beautiful experience, and Peganum on its own is active and worth a try though you need 10 grams and more to let it be visionary without addition of another substance.

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lockjaw 2012-01-04

Needed to figure out the right dose at first but other then that it was great! worked with dmt shrooms and weed and even added something to the shrooms besides just doubling their potency:P

lab 2011-12-29

Excellent MAO-Inhibitor! Jurema's and mushroom's best friend!!

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